Product Specification:
| Alternative Name: | Proteasome assembling chaperone-3 |
| Clone: | EX-7 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Immunogen: | Recombinant full length human PAC3. |
| UniProt ID: | Q9BT73 |
| Species reactivity: | Human |
| Applications: | IP, WB |
| Formulation: | Liquid. In PBS containing 0.09% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -80°C |
| Scientific Background: | The assembly of mammalian 20S proteasomes is an ordered multi-step process, starting from a-ring formation, that is in part mediated by the proteasome-specific chaperones PAC1 and PAC2. A third human 20S proteasome chaperone PAC3 has been identified as a component of the a-ring-PAC1-PAC2 complex. PAC3 is proposed to co-operate with PAC1-PAC2 heterodimers to orchestrate the correct assembly of 20S proteasomes. |
